Adrenaline

What is Adrenaline?

Epinephrine (also known as adrenaline, adrenalin, or β,3,4-trihydroxy-N-methylphenethylamine) is a hormone and a neurotransmitter. Epinephrine and norepinephrine are two separate but related hormones secreted by the medulla of the adrenal glands. They are also produced at the ends of sympathetic nerve fibres, where they serve as chemical mediators for conveying the nerve impulses to effector organs. The investigation of the pharmacology of epinephrine made a major contribution to the understanding of the autonomic system and the function of the sympathetic system. Epinephrine remains a useful medicine for several emergency indications. This is despite its non-specific action on adrenoceptors and the subsequent development of multiple selective medicines that target subtypes of the adrenoceptors. The word adrenaline is used in common parlance to denote increased activation of the sympathetic system associated with the energy and excitement of the fight-or-flight response. The influence of adrenaline is mainly limited to a metabolic effect and bronchodilation effect on organs devoid of direct sympathetic innervation.

In chemical terms, epinephrine is one of a group of monoamines called the catecholamines. It is produced in some neurons of the central nervous system, and in the chromaffin cells of the adrenal medulla from the amino acids phenylalanine and tyrosine.

Questions and answers on "Adrenaline"

I get very weak in the legs after drinking coffee. Do you know why?

doctor1 MD

Brief Answer:
Due to changes in adrenaline levels.

Detailed Answer:
Hello,
Thanks for posting your query.
Coffee is a nervous system stimulant and causes an increase in adrenaline levels and the person feels energetic. But after sometime the levels of adrenaline decrease and the muscles suddenly...

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Please read my medical history before reading further; I had a second catecholamine test completed the adrenaline levels are now 52.21 pg/ml and the noradrenaline 460.16 pg/ml. This was done under seated condition after a 20 minute light walk. I am still having panic attacks, especially after moderate exercise. I have two questions (1) are the catecholamine levels normal (2) should I stop the moderate exercise and do light exercise only until fully recovered.

doctor1 MD

Brief Answer:
You have normal catecholamines this time.

Detailed Answer:
Hi dear user
I have gone through your question
I can understand your concern.

The normal range for adrenaline is 0 to 900 pg/mL and for noradrenaline is 0 to 600 pg/mL.
So, i can see that this time the levels of adreneline...

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what drugs are used to treat adrenaline over load condition and what test is used to determine if there is in fact an overload of adrenaline.
Also what test is used to determine if you have premenstral dyshoria disorder

doctor1 MD

Brief Answer:
is it adrenaline burnout syndrome?

Detailed Answer:
Hi
Thanks for writing to us.
Let me try to answer both your questions separately
1. You mentioned adrenaline overload. Did your doctor mention as adrenaline burnout or XXXXXXX or cushings disease?
If he had mentioned burnout which...

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How long can adrenaline stay in the body?

I have been going to bed anxious and waking up, standing up and my pulse would go to 120 then i would feel it and it would go to 155 for 10 minutes 3 days in a row. Could this be anxiety?

I took a xanex the day before bed same thing happened for 2 more days except it only went to 130 and for about 30 seconds.

does this sound like anxiety? because if this were a heart problem i dont think the xanex would have calmed this down.

doctor1 MD

Brief Answer:
Xanax needs more time to oact!

Detailed Answer:
Hi and thank you so much for using this panel for your health queries.

I understand you heightened concerns about a possible heart condition. No one dares think of a heart disease and stays like nothing is happening. Unfortunately,...

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Have been experiencing anxiety and depression! I take The generic for toprol xl
for blood pressure! Was recently informed that this med can cause anxiety and depression! I have been on this med for quite sometime! Any advice?

doctor1 MD

Brief Answer:
Toprol and anxiety depression

Detailed Answer:
Thank you for contacting HCM with your health care concerns

I am sorry to hear that you are suffering with anxiety and depression. You are also being treated fro Hypertension with Toprol XL. Toprol XL is a beta blocker which blocks...

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I went drag racing for the first time, in a street car, I did four passes, the first one and fourth one, right after I launched my body started tightening and shaking badly, I felt as if I was going to pass out, I let off the throttle pedal for about 5 seconds. Till the symptoms went away. I was able to finish my run

doctor1 MD

Brief Answer:
This probably happened due to adrenaline rush

Detailed Answer:
Hello thanks for asking from HCM

Well most likely this happened due to anxiety attack. Any event or thing that results in adrenaline rush results in racing heart, sweating, palpitations, trembling, dryness of mouth like...

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Hi, this question is for a gynaecologist or specialist who can advise on female hormones. I am 44 yr old female, have been on the pill for close to 30 years. Currently on Dianne 35Ed. No previous problems but for last 3 months I am getting sweaty and hot skin surface and now body odour for the first time in my life. These symptoms haven't been everyday and they occur in the afternoon for about 4 hours then stop. Thyroid test was normal although I am type 1 diabetic with Hashimotos Disease. Is this menopause? Note my hormone bloods were as follows -
FSH - 3 IU/L
LH - 2.7 IU/L
Oest 2 - <70 nmol/L
Prog - 1 nmol/L
My Gp said likely menopause is cause.
But I was told earlier that when on the pill you don't get menopause symptoms. Also I thought levels are meant to be low when on the pill and I thought to do accurate check of hormones you have to be off the pill for a minimum of 3 months before testing.
Please advise whether these symptoms and tests show menopause and also if there is any other reason for this on off days of sweat and odour in the afternoons. I take insulin, Pravachol, Oroxine, nexium and dianne 35Ed. Have never had odour issues in my life, always shower 3 times a day and maintain strict hygiene methods and now I look sweaty, feel all sticky and clammy in armpits, neck and head and have bad odour which smells like armpit odour yet my armpits smell of deodorant so I can't even work out where smell is but it isn't good. Nb clothes don't stink either. Please help.

doctor1 MD

Brief Answer:
Not related to menopause.

Detailed Answer:
Hello,
Thanks for trusting us with your health concern.
Elevated follicle-stimulating hormone (FSH) levels are measured to confirm menopause. When a woman's FSH blood level is consistently elevated to 30 mIU/mL or higher, then it is...

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So I have normal blood pressure during the day, my numbers sitting are mid to low 120s over 80s and high 70s, the part that worries me a little, when I go to LAY down my bp is 105 to 90 over 50s. I am 31, just quit smoking 3 weeks ago. Should I be worried about this? Not much info on the web about this.

doctor1 MD

Brief Answer:
There is nothing to worry about!

Detailed Answer:
Hello!

Welcome and thank you for asking on HCM!

Regarding your concern, I would explain that this is a normal physiological reaction of the body, that happens in every healthy individual.

You should know that during physical activity...

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Hey doctor,

I am a 20 year old male and for the last year now I have been having stomach pains and digestion problems. The main symptoms I have been having are:

- Stomach pain right in the center and abdominal pains on the lower left side where pointed in the image.
- Painful chest pains
- Occasional acid reflux and heartburn
- Nausea
- Loss of weight I have lost about 6kg in the last 6 months for no reason down from 58kg to 52kg currently.
- Alternation between diarrhea and normal stools.
- Sometimes greasy and foul-smelling stools.
- Bad acne flareups
- Have developed bad anxiety because of all of this

I have been through numerous blood tests along with an ultrasound and endoscopy/colonoscopy and they have come up with nothing major but I did notice looking through them that my zinc and iron where on the very low end of the acceptable range

Another thing that I also recently I have noticed when I have alcohol only one small 600ml can like the other day for example that ever since then I have had this dull painful ache under my left ribs and I have attached an image pointing to exactly where is there any way I can alleviate this pain a little? What organ is located here and what could be the source of my pain could it maybe pancreas related? I have also been reading up about this disease called SIBO and how it is caused by low stomach acid and I have tried to cut out gluten, dairy, wheat and soy the last couple of weeks to see if that will help but the loss of weight is the biggest concern for me and a lot of people seem to notice it as well.

Medications I have tried are Zantac, Nexium, antacids which all make my symptoms a lot worse I have also tried antispasmodic which made me feel sick as well.

About 2 years ago I had this bad ear infection that didn't go away and I was on 5-6 antibiotics and I feel that is where all of this started and my mother and her father have the exact same symptoms and problems.

My diet growing up was never really the best either with a lot of processed and junk food which I feel contributed to this problem as well.

Would you have any recommendations of foods, diet, and supplements to try to based on all of this and maybe something to alleviate the pain under my ribs that goes around my back as well?

In terms of that stomach pain I get in the middle there are certain foods that trigger it and they are

Fatty foods
Onions
Garlic
Cucumber
Wheat Bread
Dairy

And that pain I get on the lower left side with the image I have attached seems to always be triggered by alchool.

I always seem to be running on adrenaline as well always sort of pumped up because I don't really feel like I get my energy from when I eat foods.

IMG_4567.JPG where I am pointing I have noticed that when I do a deep breath in it hurts there along with if I do a fake cough that it hurts in that spot. I also forgot to mention that I struggle to eat larger meals I feel as if the food just sits in my stomach especially meat.

doctor1 MD

Brief Answer:
Would like to treaty you on guidelines of IBS with overlapping gastritis.
Read the expaination patiently.
Take a print out consult your gastroenterologist.
Ask him for a prescription.
It won't help you in a day or two it would take time and life style change but i assure you that...

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What could cause a sudden spike in BP. Yesterday my BP was 129/68. Today it registered 178/82. I have no symptoms of any other problem.

doctor1 MD

Brief Answer:
I would explain as follows:

Detailed Answer:
Hello!

Welcome and thank you for asking on HCM!

Regarding your concern, I would explain that this spike in blood pressure values could be related to physical or emotional stress.

Have you been anxious today? Have you performed any...

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Recent questions on  Adrenaline

doctor1 MD

I HAD OPEN HEART SURGERY 6 WEEKS AGO SINCE THE SURGERY MY HANDS ARE CONSTANTLY SHAKING

doctor1 MD

Hey doctor, I am a 20 year old male and for the last year now I have been having stomach pains and digestion problems. The main symptoms I have been having are: - Stomach pain right in the center and abdominal pains on the lower left side where...

doctor1 MD

I am hoping someone can help me and shed some light on something that has been going on for me. I feel lost and scared. About 9 months ago, I started getting this dizzy sensation when tilting my head to the right but only sometimes. And sometimes,...

doctor1 MD

Yes, thank you. My Husband has just discovered a split root under a crown which due to the position and the fact that it cannot be easily accessed - he will require involved oral surgery. He is more than a little worried about the adrenalin used during this lengthly procedure. Due to his medication (age 67) this use of adrenalin could cause a 'bushfire' or a stroke/hypertension - what are his options, and would he be safe in ceasing any regularly taken meds in preparation or during the lead up to such a procedure? Georgia C. Feller

doctor1 MD

my son is 6m old & he had been asked to be nebulised every 4hrs with adrenaline 0.6ml with 2.5ml 3% hypertonic ns & budecort respule every 12hrs i had been nebulising him for past 15 days regularly & the dr had asked to do so for next 7days is it safe to use nebuliser for so long in case of such small infant & also let me know whether nebuliser is habit forming or not in the long run

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