Hello there.
Now that your wife's blood test shows
salmonella infection, it means she is having typhoid.
Typhoid infection by itself is not teratogenic (damaging to baby). Its effects on pregnancy are because of high grade fever associated with typhoid. All high grade fevers are uterine stimulant and fetotoxic. These effects can precipitate preterm labour(premature delivery) and intra-uterine death (death of baby in uterus).
So the main aim is to bring down temperature in fever. You should keep a record of her temperature. Whenever she is febrile ( temperature more than 37degrees) you should bring it down with the help of tepid sponging and antipyretics.
Paracetamol is safe in pregnancy to bring down temperature.
The definitive managemnt of typhoid involves use of antibiotics. The safest antibiotic for treating typhoid in pregnancy is a
cephalosporin eg ceftriaxone.
Ciprofloxacin should be avoided as its not safe in pregnancy.
Other supportive measures you should take are:
1. Drinking plenty of fluids. This helps prevent the
dehydration that results from a
prolonged fever and diarrhea.
2. Eating a healthy diet. Nonbulky, high-calorie meals can help replace the nutrients you lose when you're sick.
3. Since she is in her first trimester, she has to continue taking
folic acid tablet daily which is a must in every pregnancy.
4. Ultrasound should be done once she recovers from the typhoid to ensure baby's well being.
All the best.