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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Terrible Nausea, Vomiting. On Phenergan Po. Constant Diarrhea After Taking Prescribed Suppositories. Okay To Take Phenergan Suppository Vaginally?

I am a nurse and we all know we are the worst patients. I have a long standing history of Crohn's Disease diagnosed in 1992 with 2 previous surgeries. I had a terrible episode of nausea and vomiting on Monday and I take Phenergan po frequently because I pretty much live with constant nausea. Since I was unable to keep anything down my physician ordered suppositories. My nausea is still worse than my baseline so I have used the suppositories instead of po. I now am having diarrhea constantly as of yesterday and today which is pretty normal to me but I know a suppository would not stay in and I would get no relief because I have gone to the bathroom 6 times since 7am. I worked for hospice many years and at the end of a patient's life when they were unable to swallow we would often give some meds rectally. So, sorry for all of the back story but do you feel it would be ok to take the phenergan suppository vaginally?
Mon, 19 Aug 2013
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General Surgeon 's  Response
hello
first of all i will like to inform you as you are nurse that phenergen is anticholinergic drug which increase gut motility so its absorption is also unpredictable from other route so please take medicine as per your physician advice also you can change your medicine by your physician advise. skin (epithilium) of vagina is very different type and its not help you in drugs absorption.
god bless you
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Terrible Nausea, Vomiting. On Phenergan Po. Constant Diarrhea After Taking Prescribed Suppositories. Okay To Take Phenergan Suppository Vaginally?

hello first of all i will like to inform you as you are nurse that phenergen is anticholinergic drug which increase gut motility so its absorption is also unpredictable from other route so please take medicine as per your physician advice also you can change your medicine by your physician advise. skin (epithilium) of vagina is very different type and its not help you in drugs absorption. god bless you