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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is There Any Treatment For Y-chromosome Inversion ?

Hi,

In my chromosome analysis it was found that my Y-chromosomes were inverted. My wife had 2-3 miscarriage in last 3 years. We are doubting that Y-chromosome inversion could be the reason of the same.

Is there any treatment of this problem (Y-chromosome inversion)?

Should we try for baby before treatment of this problem?

 

Regards,

Dev

Fri, 2 Sep 2011
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Nephrologist,  's  Response
Thanks fr the query
Inverted Y chromosomes does not impede the production of normal sperm and does not predispose to nondisjunction of other chromosomes in the progeny. Thus, the earlier concept of nondisjunction was rejected, and it is suggested that aberrant cases with aneuploldy and an inverted Y are fortuitous. The pericentric inverted Y is inherited from generation to generation and has no clinical significance The prevalence of males with pericentric Y inversion in the general population is approximately 1 per 1000. It is suggested that a periceniric inversion of the Y chromosomes is a rare chromosomal heteromorphism.

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Is There Any Treatment For Y-chromosome Inversion ?

Thanks fr the query Inverted Y chromosomes does not impede the production of normal sperm and does not predispose to nondisjunction of other chromosomes in the progeny. Thus, the earlier concept of nondisjunction was rejected, and it is suggested that aberrant cases with aneuploldy and an inverted Y are fortuitous. The pericentric inverted Y is inherited from generation to generation and has no clinical significance The prevalence of males with pericentric Y inversion in the general population is approximately 1 per 1000. It is suggested that a periceniric inversion of the Y chromosomes is a rare chromosomal heteromorphism. Have a healthy living