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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Colonoscopy Found Intestine Has Melanosis Coli. Cascara Sagrada Is Doing It?

hello, I am from Brasil and recently in a colonoscopy last year, I found out that my intestine has melanosis coli and the doctor asked me if I have been taking laxatives for a long time. I have not but I do take an American Circulatory supplement for my legs circulation called Circulegs for the past 2 years everyday (twice a day) and it has Cascara Sagrada in it. Do you think the Cascara Sagrada is doing it?
Mon, 10 Jun 2013
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  User's Response
Hi,

The answer to your question is yes - Cascara can cause this.

Melanosis coli is most commonly caused by laxative abuse. Cascara sagrada used to be classified by FDA as an over-the-counter laxative until November 2002 when FDA removed it because of some safety and effectiveness concerns. Since 2002, Cascara is sold as a dietary supplement (dietary supplements do not have to be approved by FDA).

Hope this helps.

Kind regards
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Colonoscopy Found Intestine Has Melanosis Coli. Cascara Sagrada Is Doing It?

Hi, The answer to your question is yes - Cascara can cause this. Melanosis coli is most commonly caused by laxative abuse. Cascara sagrada used to be classified by FDA as an over-the-counter laxative until November 2002 when FDA removed it because of some safety and effectiveness concerns. Since 2002, Cascara is sold as a dietary supplement (dietary supplements do not have to be approved by FDA). Hope this helps. Kind regards