Sign-in to Ask A Doctor - 24x7
OR
Sign in with GoogleGet your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
What Is Imuran? What Has Caused Hemolytic Anemia?
I have been diagnosed with hemlytic anemia and this is the 2nd time I had to have blood transfusions. I am then treated with prednisone and imuran. What is imuran and what has caused this anemia. No one in family has had any condition like this however I do take alot of medications. What medications will cause this?
Thu, 13 Mar 2014
Hi
Hemolytic anaemia may be classified according to the means of hemolysis, being either intrinsic in cases where the cause is related to the red blood cell (RBC) itself, or extrinsic in cases where factors external to the RBC dominate.Intrinsic effects may include problems with RBC proteins or oxidative stress handling, whereas external factors include immune attack and microvascular angiopathies (RBCs are mechanically damaged in circulation).
Immune-mediated causes could include transient factors as in Mycoplasma pneumoniae infection (cold agglutinin disease) or permanent factors as in autoimmune diseases like autoimmune hemolytic anemia (itself more common in diseases such as systemic lupus erythematosus, rheumatoid arthritis, hodgkin disease and chronic lymphocytic leukemia)
Treatment includes blood tranfusion in severe anaemia and sometimes immunosuppressive treatment in autoimmune diseases,with prednesoline or azathioprine(imuran)
Azathioprine is an immunosuppressive drug used in organ transplantation and autoimmune diseases and belongs to the chemical class of purine analogues
Hemolytic anaemia may be classified according to the means of hemolysis, being either intrinsic in cases where the cause is related to the red blood cell (RBC) itself, or extrinsic in cases where factors external to the RBC dominate.Intrinsic effects may include problems with RBC proteins or oxidative stress handling, whereas external factors include immune attack and microvascular angiopathies (RBCs are mechanically damaged in circulation).
Immune-mediated causes could include transient factors as in Mycoplasma pneumoniae infection (cold agglutinin disease) or permanent factors as in autoimmune diseases like autoimmune hemolytic anemia (itself more common in diseases such as systemic lupus erythematosus, rheumatoid arthritis, hodgkin disease and chronic lymphocytic leukemia)
Treatment includes blood tranfusion in severe anaemia and sometimes immunosuppressive treatment in autoimmune diseases,with prednesoline or azathioprine(imuran)
Azathioprine is an immunosuppressive drug used in organ transplantation and autoimmune diseases and belongs to the chemical class of purine analogues
I find this answer helpful
1 Doctor agrees with this answer
Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer.
For a more detailed, immediate answer, try our premium service
[Sample answer]
Related questions you may be interested in
Recent questions on Chronic lymphocystic leukemia
Loading Online Doctors....