Uncomfortable pressure, fullness, squeezing or pain in the center of the chest lasting more than a few minutes. Pain spreading to the shoulders, neck or arms. The pain may be mild to intense. It may feel like pressure, tightness, burning, or heavy weight. It may be located in the chest, upper abdomen, neck, jaw, or inside the arms or shoulders. Chest discomfort with lightheadedness, fainting, sweating, nausea or shortness of breath. Anxiety, nervousness and/or cold, sweaty skin. Increased or irregular heart rate.