atherosclerotic plaque formation:
excess LDL cholesterol is oxidized by free radicles & then taken up (phagocytosed) by macrophages (tissue monocytes) & transform into faom cells that start secreting substances promoting endothelial cell prolifration (endothelium = cells lining the inside of vesseles).. foam cells accumulate over injured endothelium and form "fatty streaks"..which progress into the atherosclerotic plaque.....
anatomy...there is the left main coronary artery & the right coronary artery..all arising from the ascending aorta..just above the aortic valve...cardiac (heart) perfusion occures during diastole ( heart relaxarion) (not as the rest of the body..during systole ( heart contraction)..
if u want further info on the coronary anatomy..just ask..
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