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Zexter injection given for high WBC. Bone marrow test showing myeloid hyperplasia, dysplastic change in granular cells. Explain?

Hi my name is mohammed and i am 25 years old 4 days ago i did CBC test and it shows that my WBC was 0000 and doctor gave me Zexster injection and after that i did bone morrow and it show this:
Myeloid hyperplasia,sheft to right,granular cells represent in about 59% with dysplastic change
Aniso Pickilocytosis
leukocytosis neutrophilia
please help me what is mean?
Asked On : Fri, 12 Apr 2013
Answers:  1 Views:  57
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Pathologist and Microbiologist 's  Response
Hello and welcome to HCM,

Your hemogram and bone marrow report reads that there is myeloid hylerplasia. Myeloid cells include cells other than lymphocytes. This includes neutrophils, eosinophils, basophils and monocytes.
An increase in any of these cells is called myeloid hyperplasia.
Shift in left means that the mature cells in the myeloid series are increased.
In myeloid series (neutrophil series) immature cells to mature cells are present.
When there is increase in mature cells it is called shift to right.
When there is increase in immature cells, it is called shift to left.
Increase in mature neutrophils occurs in bacterial infections and certain malignancies (eg chronic neutrophilic leukemia).
Presence of dysplastic cells need to be investigated.
Anisopoikilocytosis is the condition when there is variation in shape and size of the red blood cells.
This usually occurs in anemias.
You need some more investigations to know the cause of anemia and neutrophilia.
Stay in touch with your hematologist for relevant investigations and appropriate management.

Thanks and take care
Dr Shailja P Wahal .

Answered: Tue, 25 Jun 2013
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