My husband has genital herpes and was recently diagnosed with colon cancer. He received 1 treatment of chemotherapy and has run a fever everyday for about 2 weeks. About five days after his treatment he noticed discomfort of the scrotum. It was red on both sides and had areas of what appeared to be pus filled lesions. Could this be a side effect of the chemo or is this an outbreak. He is taking valtrex and applying a cream. It seems to be improving slowly. Should he tell his oncologist about the herpes. Will it effect his treatments and does chemotherapy increase the severity of outbreaks.