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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Will Taking Tamoxifen Has Any Side Effect On Brain?

I was on Aromasin for 4 years and am supposed to be on tamoxifen but was tired of these drugs. I am now going to start taking the tamoxifen. How will the side effects impact my brain? I am in an EMBA program...I HATED the confusion brought on by Aromasin. Can I expect something similar? How can I mitigate brain impact?
Tue, 18 Oct 2016
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Neurologist,  's  Response
Hello! Tamoxifen has another mechanism of action comparing to aromasin, but both have an aim, to reduce the estrogen effect on breasts. Confusion as a direct side effect is registered for none of the drugs. The most frequent side effects of tamoxifen are the hot flashess, vaginal discharges, menstrual disturbances. Depression and fatigue are found in less than 2% and 4% of people using tamoxifen. Meanwhile, with the use of aromasin, fatigue and depression are the side effects seen more often. Other frequent side effects of aromasin are anxiety and insomnia. Tamoxifen does not have any other side effect (at least studied ones) that can give you the confusion that you felt by aromasin. Confusion as a direct side effect is registered for none of the drugs.
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Will Taking Tamoxifen Has Any Side Effect On Brain?

Hello! Tamoxifen has another mechanism of action comparing to aromasin, but both have an aim, to reduce the estrogen effect on breasts. Confusion as a direct side effect is registered for none of the drugs. The most frequent side effects of tamoxifen are the hot flashess, vaginal discharges, menstrual disturbances. Depression and fatigue are found in less than 2% and 4% of people using tamoxifen. Meanwhile, with the use of aromasin, fatigue and depression are the side effects seen more often. Other frequent side effects of aromasin are anxiety and insomnia. Tamoxifen does not have any other side effect (at least studied ones) that can give you the confusion that you felt by aromasin. Confusion as a direct side effect is registered for none of the drugs. I hope i have been of help.