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Dr. Andrew Rynne
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Will taking Duphaston on the 14th day of the cycle hinder ovulation?

Hi, m 30 years old, weight 68 Kg Height 5.2 feet married for 7 years had two abortions my question is from gynaecologist : I m a dioagnosed case of PCOS , and have very irregular periods almost once in 3 to 4 months, i am trying really hard to lose weight under dr's supervision but thats also not working. My O n G has prescribed me Tab Duphaston from 14th day to 25th day of evey cycle for six months. My question is as my cycle is not regular and ovulation does not occur on 14th day of cycle so is there any chance that taking duphaston on 14th day of every cycle can stop or hinder ovulotion to occur? and also how can i reduce the risk of endometrial carcinoma and other risks associated with PCOS in old age?
Fri, 25 Jul 2014
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General & Family Physician 's  Response
Hello and Welcome to ‘Ask A Doctor’ service.

I have reviewed your query and here is my advice. You are having Poly Cystic Ovarian Syndrome (PCOS). I want to explain you few sign and symptoms of pcos. PCOS is recognised as an entity occurring in young females with chronic anovulation with estrogen presence and having the following symptoms:
1. Androgen excess amnifesting as hirsutism and acne.

2. Menses irregularities, dysfunctional uterine bleeding or amenorrhea (as in your case irregular bleeding present with amenorrhea).

3. Obesity with glucose intolerance (as you are having over weight, so this is due to pcos).

Lab reports:

1. Alteration in LH/FSH ratio.
2. Elevated serum testosterone level
3. Ultrasound findings, of atretric follicles with increased ovarian stroma.

I mentioned all these so that you can understand more about your disease. Duphastone, for example dydrogesterone is also prescribed for irregular bleeding, for infertility, dysfunctional uterine bleeding, and endometriosis.

So your doctor prescribed a right dose for your case because you are having irregular bleeding, amenorrhea, and infertility. Duphastone is also indicated for endometriosis. So take this drug and consult your doctor for infertility or another infertility specialist.

Hope I have answered your query. Let me know if I can assist you further.

Good luck.

Dr. Het Ram Bishnoi
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