Hi Manju, Thanks for writing your query. Seroflo Rotacaps contains Salmeterol and Fluticasone. Salmeterol is long acting bronchodilator and Fluticasone is a steroid. Prolonged use of rotacaps will not cause dependence but rather it helps in decreasing the symptoms of bronchitis. Side effects are minimal as the route of medicine is through inhalation and not through absorption in blood. When the medicine is inhaled it directly reaches its target i.e. the air way including the bronchioles. So the effect of using rotacaps is more beneficial and there is no dependence. I hope this is helpful to you. Thanks.