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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Will Candid Cl And Oflomac Oz Have Any Effect On Foetus ?

Hello Doctor, My wife, she had taken the following tablets for yeast infection, 1. Candid cl (Consumed tablet quantities are 3nos), 2. Oflomac oz (Consumed tablet quantities are 10 numbers) for almost 5days in third week of her period cycle(8th Dec to 13th Dec 2013). Today (22nd Dec 2013), we met our doctor and came to know that My wife is pregnent (Today 32nd day from the last period time). Now, we want to know that whether the above taken medicine will affect the foetus?. Please provide your valuable advise. Thanks and Regards Alex S
Thu, 26 Dec 2013
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General & Family Physician,  's  Response
HI. welocmeE to HCM. Candid CL contians clindamycin and clotrimazole, it is usualyy prescribed to treat candida infection, This drug is safe during pregnancy under medical supervision. Oflomac OZ contains ofloxacin and ornidazole. It does have some sideeffects on bones and cartilage hence best avoided during pregnancy however some doctors do prescribe it if absolutely necessary (where benefits outweigh the risks). Futher details of this Ofloxacin( fluroquinolones ) use in Animal studies using high doses have revealed evidence of fetotoxicity and teratogenicity. Rarely fetal exposure to fluoroquinolones has been associated with myelomeningocele, hydrocephaly, hypospadias, maldescended testes, inguinal hernia, bilateral hip dysplasia, and atrial septal defects. Because safer alternatives are available, some experts consider ofloxacin contraindicated during pregnancy, especially during the first trimester. In the second and third trimesters, when the potential risk for to cause birth defects is less, it can be considered. However these drugs if taken it should be strictly under medical supervision. All the best
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Will Candid Cl And Oflomac Oz Have Any Effect On Foetus ?

HI. welocmeE to HCM. Candid CL contians clindamycin and clotrimazole, it is usualyy prescribed to treat candida infection, This drug is safe during pregnancy under medical supervision. Oflomac OZ contains ofloxacin and ornidazole. It does have some sideeffects on bones and cartilage hence best avoided during pregnancy however some doctors do prescribe it if absolutely necessary (where benefits outweigh the risks). Futher details of this Ofloxacin( fluroquinolones ) use in Animal studies using high doses have revealed evidence of fetotoxicity and teratogenicity. Rarely fetal exposure to fluoroquinolones has been associated with myelomeningocele, hydrocephaly, hypospadias, maldescended testes, inguinal hernia, bilateral hip dysplasia, and atrial septal defects. Because safer alternatives are available, some experts consider ofloxacin contraindicated during pregnancy, especially during the first trimester. In the second and third trimesters, when the potential risk for to cause birth defects is less, it can be considered. However these drugs if taken it should be strictly under medical supervision. All the best