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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Will antitubercular drug cause infertility?

iwas on antitubercular drug since two months after i was suffering from infertility for three years for endometriel tuberculosis. i missed my period seven days ago and my urine pregnancy test became positive today. Should i continue the antitubercular drugs and what are the chances of ill effects of the drugs on my pregnancy ?
Thu, 25 Jun 2020
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General & Family Physician 's  Response
Hi,

All 4 first line drugs isoniazid, rifampicin, ethambutol and pyrazinamide have a safety record in pregnancy and are not associated with human fetal malformations. But the use of drugs should be decided based on the benefits and risk, previous duration of treatment and clinical condition and Category of tuberculosis.

I would suggest you to visit your doctor for a clinical examination and decide the course of treatment. Aminoglycosides such as Streptomycin. Kanamycin. Amikacin should be absolutely avoided in pregnancy.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Saranya Ramadoss, General & Family Physician
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Will antitubercular drug cause infertility?

Hi, All 4 first line drugs isoniazid, rifampicin, ethambutol and pyrazinamide have a safety record in pregnancy and are not associated with human fetal malformations. But the use of drugs should be decided based on the benefits and risk, previous duration of treatment and clinical condition and Category of tuberculosis. I would suggest you to visit your doctor for a clinical examination and decide the course of treatment. Aminoglycosides such as Streptomycin. Kanamycin. Amikacin should be absolutely avoided in pregnancy. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Saranya Ramadoss, General & Family Physician