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Wife family has history of schizophrenia. Any test to find out during pregnancy the early stage of schizophrenia ?

Dear Dr. Srikanth Reddy, Psychiatrist , My wife family has history of schizophrenia ( Her family consist of mother ( schizophrenic got from her uncle ), father(Perfect including his family history), 1 elder sister (schizophrenic) and 2 elder brothers( 1 bro is schizophrenic, another one perfect) )...In my family including both father side and mother side we dont have any history of mental illness ... My wife and I are not having any mental disorder ..Hence we both do not use any kind of psychotropic medicence(pills) ... My wife does not have high blood pressure/blood sugar/tyroid. My wife has been taking folic acid from last 2 months .Now from last 15 days she has started T-Biopreg and while taking this tablet she avoids folic acid as this tablet has folic acid.Along with this we both takes a piece of walnut including other dry fruits. We are trying to maintain healthy diet too. However we need your suggestion to make sure we are on right path..please suggest.. My questions is : 1. Do we have genetic test available globally( Anywhere in india or across the globe ) that can be carried any stage of life i.e during pregnancy, post pregnancy or in adult identify schizophrenia earlier .Please confirm and suggest. 2. I have heard of B12 good for brain..Can my wife takes bicosule capsules along with Biopreg?? My wife had MTP on july 2012 becouse she had taken some antibiotics (fynaloz 9levofloxacin)--2 tabbs, azee 500mg --3 tabs, cetirizine, betnesol- 5 tabs) during first month of her pregnancy as she was not knowing she was pregnant. Now we are planning to have baby after march 2013.If you can suggest what best we can eat, execise, prenatal ills that most suit in our case. Thanks
Asked On : Sat, 19 Jan 2013
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OBGYN 's  Response
Mar 2013
Thank you for your query.
There is NO TEST available in India or anywhere in the world that can diagnose schizophrenia during pregnancy, post pregnancy or early infancy.
Schizophrenia has multifactorial causes, and has been suspected to have a genetic predisposition, but no causative gene has been pinpointed, and hence no screening test is available.
The diagnosis is also made clinically, and not by a genetic test.
You have not mentioned the weeks of pregnancy.
If she is in her first trimester, only folic acid and vitamin B 12 capsules can be taken.
It is very essential to have a healthy diet rich in antioxidants - green leafy vegetables, nuts, grains, legumes etc.
In the second and third trimester, she needs iron, calcium, vitamin D and good amount of protein in the diet.
Moderate exercise in the form of daily walking for 45 minutes is best.
In late pregnancy, she can attend pelvic exercise classes.
It is a good ideal to enrol in antenatal classes for proper antenatal care.
Avoid exposure to smoking/drinking/radiation/drugs/toxins/caffeine etc.

Go for appropriate genetic tests to detect abnormalities in the baby at various intervals as suggested by your gynecologist.
Take care.
Answered: Fri, 15 Feb 2013
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