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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Why are Clarithromycin and Carbocisteine taken during pregnancy?

hi i take clarithromycin and carboceistine during my first month of pregnancy or should i say 1 or 2 weeks of it. I am not aware that i am pregnant that time so after my check up i took those medicines as my doctor recommended. now i am very worry about the effect of those medicines...please help me to answer my questions. thank you very much
Thu, 31 Dec 2015
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OBGYN 's  Response
hello,
I have gone through your query. Here are your answers: 1. Clarithromycin has been shown to cause adverse effects in the fetus in animal studies at doses with serum levels 2-17 times that achieved in humans. Hence, it should be used only if absolutely needed. 2. Carbocisteine is preferably avoided in pregnancy, though no controlled studies are available to establish fetal harm. It is unfortunate that you took both the medications unknowingly. Please report to your gynecologist to plan further management. Fetal DNA tests can reveal some deformities and this is the earliest test available. Anomalies scan, chorion villus biopsy and amniocentesis are the other methods available to detect fetal anomalies. Hope your query has been answered. Take care.
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Why are Clarithromycin and Carbocisteine taken during pregnancy?

hello, I have gone through your query. Here are your answers: 1. Clarithromycin has been shown to cause adverse effects in the fetus in animal studies at doses with serum levels 2-17 times that achieved in humans. Hence, it should be used only if absolutely needed. 2. Carbocisteine is preferably avoided in pregnancy, though no controlled studies are available to establish fetal harm. It is unfortunate that you took both the medications unknowingly. Please report to your gynecologist to plan further management. Fetal DNA tests can reveal some deformities and this is the earliest test available. Anomalies scan, chorion villus biopsy and amniocentesis are the other methods available to detect fetal anomalies. Hope your query has been answered. Take care.