Hi, Folic acid is essential for neural tube defects in the developing fetus. Neural tube is the basic structure in the fetus that leads to the development of brain in a child. Failure to take folic acid supplements can cause major birth defects to the spinal cord and improper brain and skull development. Hence, it is suggested to take folic acid right from the time of planning for pregnancy and continue till first trimester. I would suggest you to take folic acid regularly since it is very essential. You can take the drug after food to reduce nausea or vomiting which can commonly occur as a side effect. You can take the drug at night after dinner so that you can avoid the discomfort at day time. Drink plenty of fluids to hydrate your body. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Saranya Ramadoss, General & Family Physician