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Dr. Andrew Rynne

Family Physician

Exp 18 years

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What treatment should I take for mthrfr mutation post a surgery for clot and a family history of DVT ?

2yrs ago a clot was found in my left femoral.I was placed on Warfarin and had an IVC filter placed,prior to a surgical procedure.It took nearly a year @ 10mg per day to get my INR to 1.3. The first clot was resolved but more were found.Recently I moved to FL and my new GP diagnosed me w polycythemia,based on the levels of my lab results.Then I went to a hemotologist who says its not poly... but I do have the mthrfr mutationWhat is going on, what can I do?,my Mother a pulmonary embolism,. My Grandmother died of a stroke,my brother is currently being treated for a clot in his calf, and worst of all my 12 yr old nephew had to be airlifted to LomaLindaChildrens after a clot was found in his neck.He tested positive for the leiden factor.I was negative. i would really appreciate any info on what it is Im dealing w.I also have a daughter who seems well but has not been tested,yet. I turned 40 2 days ago.I dont mean to bombard you,I hope you understand and appreciate that I am desperate for info. Unfortunately the drs here are giving me conflicting opinions and info. PLEASE HELP!!!
Thu, 12 Jan 2012
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General & Family Physician 's  Response
Hi, Welcome to HealthcareMagic Forum.
May be you are suffering from Homocystinuria, you should be getting yourself examined by a Physician. It runs in families and it is a Genetically Inherited Disorder. You may require high doses of Vitamin B6 (Pyridoxine).
A normal dose of folic acid supplement and added cysteine (an amino acid) in the diet is also helpful.
Kindly see your Doctor at the earliest as you need immediate medical attention.

Wish you Good Health and Take Care.
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