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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Treatment Is Required To Treat Chronic Inflammatory Demyelinating Polyneuropathy And IgA Deficiency?

Hello Doctor, My Son has just been diagnosed with CIDP and igA deficiency. I would like information on these types of diseases and what is the best treatment for the diseases he has. He has already lost 85% of the muscles in his
legs and 75% in his hands & arms. He also has started having tremors and is shaking like he is cold but he is not cold.
Thank You, Joanne Love
Tue, 24 Dec 2013
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General & Family Physician 's  Response
Hello,
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired immune-mediated inflammatory disorder of the peripheral nervous system.
It cause damage to the myelin sheath (the fatty covering that wraps around and protects nerve fibers) of the peripheral nerves.
Available treatment options are
1. Corticosteroids such as prednisone, which may be prescribed alone or in combination with immunosuppressant drugs.
2. Plasmapheresis (plasma exchange) and intravenous immunoglobulin (IVIg) therapy are effective.
IVIg may be used even as a first-line therapy.
3. Physiotherapy may improve muscle strength, function and mobility, and minimize the shrinkage of muscles and tendons and distortions of the joints.

IgA deficiency- People with this deficiency lack immunoglobulin A (IgA), a type of antibody that protects against infections of the mucous membranes lining the mouth, airways, and digestive tract.
He may have increased frequency of infections, particularly in the respiratory, digestive and genitourinary systems, for example, sinusitis and urinary tract infections.
There is no treatment for the IgA deficiency.
But he need
1. Proper identification of co-morbid conditions
2. preventive measures to reduce the risk of infection
3. prompt and effective treatment of infections

Hope this helps.
Please write back for further queries.
Wishing you good health.
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What Treatment Is Required To Treat Chronic Inflammatory Demyelinating Polyneuropathy And IgA Deficiency?

Hello, Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired immune-mediated inflammatory disorder of the peripheral nervous system. It cause damage to the myelin sheath (the fatty covering that wraps around and protects nerve fibers) of the peripheral nerves. Available treatment options are 1. Corticosteroids such as prednisone, which may be prescribed alone or in combination with immunosuppressant drugs. 2. Plasmapheresis (plasma exchange) and intravenous immunoglobulin (IVIg) therapy are effective. IVIg may be used even as a first-line therapy. 3. Physiotherapy may improve muscle strength, function and mobility, and minimize the shrinkage of muscles and tendons and distortions of the joints. IgA deficiency- People with this deficiency lack immunoglobulin A (IgA), a type of antibody that protects against infections of the mucous membranes lining the mouth, airways, and digestive tract. He may have increased frequency of infections, particularly in the respiratory, digestive and genitourinary systems, for example, sinusitis and urinary tract infections. There is no treatment for the IgA deficiency. But he need 1. Proper identification of co-morbid conditions 2. preventive measures to reduce the risk of infection 3. prompt and effective treatment of infections Hope this helps. Please write back for further queries. Wishing you good health.