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Dr. Andrew Rynne

Family Physician

Exp 50 years

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What measures can one take to avoid miscarriage ?

Hi im 23yrs old and i ve been pregnant four times and I had my first misscarriage at 6months when I was 19. I did not know I was pregnant and every test read negative..and so on for two year I have had a misscarriage and even the doctors test read negative but whenever they draw blood it will be positive and my stomach is getting huge and im scared that im pregnant but all the test say negative! What can I do and should I do?
Fri, 27 Jan 2012
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General & Family Physician 's  Response
Hi welcome to healthcare magic forum

Since the urine pregnancy tests comes negative, its better to get USG scanning to rule out pregnancy... The UPT is an antibody mediated test, for anti body to be produced, it takes atleast a week...
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doctor1 MD

History : My sister (Age 32) under gone three repeated miscarriages • First miscarriage happened in 2nd month • Second miscarriage happened in 4th month • Third miscarriage happened in 4th month After third miscarriage we undergone some of the tests suggested by the doctor and below are the details Date : 28 July 2010 Tests undergone first time after three miscarriages Lupus Anticoagulant 1 (Screen) 53 sec (Normal 28-45) Lupus Anticoagulant 2 (confirm) 58 sec (Normal 28-40) Ratio (LA1/LA2) 0.91 ( 1.3 Normal) A.P.T.T TEST 38 sec (result) (Normal 30-40 sec) CONTROL 24 sec (result) (Normal 30-40 sec) ANTI CORDIOLIPIN ANTIBODIES CARDIOLIPIN ANTIBODY – lgM 9.67 PL-lgM-U/mL ( 10 : Negative) CARDIOLIPIN ANTIBODY – lgG 28.0 PL-lgG-U/mL ( 10 : Negative, 10-20 LOW POSITIVE 20-40 MODERATE POSITIVE) CARDIOLIPIN ANTIBODY – lgA 13.27 PL-lgA-U/mL ( 10 : Negative 10-20 LOW POSITIVE) PROLACTIN (PRL) 11.67 ng/ml (Result) (Normal Range ; Females Non-Pregnant: 2.8 – 29.2) Thyroid Stimulating Hormone ( TSH ) 1.06 ulU/mL (Result) (Normal Range 0.34-5.60 ulU/mL) FSH 6.17 mIU/mL (Result) (Normal Range (Normal Range Femal Follicular phase 2.5-10.2) Date : 28 September 2010 After 2 months medication repeated below tests Lupus Anticoagulant 1 (Screen) 32 sec (Normal 28-45) Lupus Anticoagulant 2 (confirm) 36 sec (Normal 28-40) Ratio (LA1/LA2) 0.88 ( 1.3 Normal) A.P.T.T TEST 27 sec (result) (Normal 30-40 sec) CONTROL 24 sec (result) (Normal 30-40 sec) ANTI CORDIOLIPIN ANTIBODIES CARDIOLIPIN ANTIBODY – lgM 8.71 PL-lgM-U/mL ( 10 : Negative) CARDIOLIPIN ANTIBODY – lgG 10.9 PL-lgG-U/mL ( 10 : Negative, 10-20 LOW POSITIVE ) CARDIOLIPIN ANTIBODY – lgA 7.26 PL-lgA-U/mL ( 10 : Negative) Date : 10 January 2011 Found that my sister is affected with TB undergone 6 months course for TB Date : 17 May 2011 Suggested Laproscopic surgery for better findings, after laproscopic surgery below is the discharge summary Recurrent Pregnancy loss for evaluation Operative Hysteroscopy & Laparoscopy done on 17 May 2011 At Hysteroscopy: • Both ostia visualized normally placed • Uterine cavity normal At Laparoscopy: • Uterus normal size • Both tubes normal. Dye test positive both sides. • Small fimbrial cyst present on test tube, excised. • Both overies polycystic, ovarian drilling done • POD free, No E/O adhesions or endometriosis Biopsy result Nature of Specimen: Endometrial Curettings for HPE Microscopic Examination: Sections revealed endometrial tissue with predominantly blood clots and few glands in proliferative pattern. No evidence of neoplasia or granulomas Impression: Proliferative pattern What I want to say: After three miscarriages my sister undergone above tests and some test results were not in normal range, after two months medication those readings came to normal range. And upon our request for any tests Dr. went for Laproscopic surgery and said that she has done ovarian drilling and uterus condition is good and biopsy says that TB which attacked my sister doesn’t have any effect on her uterus. And Dr also says that we need to go Ecosprin and Loprin (not sure of the correct names) injections continously till 9th month once after conceived What I want to ask: There was no specifc finding from Dr that this was the reason for 3 repeated miscarriages, to the best of my knowledge except karotyping we have completed all tests. I am seeking your suggestion in case we are missing any other tests and will be there any side affects of taking daily injections for 9months and any other suggestions/advice are invited. Our whole intension is not to have another miscarriage. Thanks in Advance

doctor1 MD

hi doctor, I had miscarriage 2 times , first miscarriage in dec 13 2014 ( around 9 weeks pregnant) and another in May 13 2015 ( around 11 weeks pregnant)..PLease guide me what I need to do to avoid this in future. second pregnancy : took seven seas tablet for two months before conceiving,then took ferrous sulphate tablet (2 tablets per day + pregnacare tablet) as per doctor advice when I was at 8th week pregnancy. I went for a scan when I was at 7 weeks and 5 days, was able to see heart beat and foetus measured around 15mm. Two days back bleeding started and had a scan it looks like heart beat stopped and foetus growth is only 17 mm for 11 weeks pregnant When I missed my period I started getting pain in my lower hip and shoulder , I had this same problem in my first pregnancy it continues till 6 weeks..whether that could be a problem for my miscarriage .. Please let me know what test do I need to take , after how many months can I plan for my next conceive. It is painful , I just pray God no one should get this problem in future.

doctor1 MD

Hi doctor. My wife is 27 years of age. We got married about 9 months ago. She had a miscarriage in the first few weeks. Now she is pregnant again. Her bhcg is a little lower than usual. She has been prescribed duphaston tabs which she had been taking regularly for the past 10 days or so. What other medicine or injections do you recommend to avoid another miscarriage. Any advice will be highly regarded. Thanks. Salman