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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Is The Treatment To Lower The SGOT And SGPT Values?

i HAVE HAD A RISE IN MY SGOT 77.0 & SGPT 83.0. VA SAID THE CATSCAN SHOWED THE BEGINNING OF FATTY LIVER.I was taking Lipitor 40mg which they said to discontinue. Follow low fat /cholesterol diet.My count has been up to when I started taking Lipitor. . Was taking Simvastatin 80 mg for years with good results & average SGOT/SGPT readings. Cholesterol reading is 130 & Triglycerides read 54 BILIBRUBIN IS A LITTLE HIGH WITH AN AVERAGE OF 1.7 .Should I see hepatologist? What should I do to get it down & is there a cure? my age is 80 in good shape.
Mon, 24 Aug 2015
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General & Family Physician 's  Response
Hello,

Thank you for your question and welcome to Health Care Magic. I read carefully your query and I understand your concerns.

Increment of liver enzymes is a known side effect of the usage of statins, which are medications used for lowering blood cholesterol. Two liver enzymes in particular (SGPT or ALT, and SGOT or AST) may be mildly elevated, but in my opinion it is safe to continue treatment unless they rise by three times the upper limit of normal and in that case the statin should be stopped. The damage is not permanent and when statins are stopped the liver tests return to normal. Normal values of SGPT are considered 5 -50 U/L and for SGOT- 7-40 U/L. Bilirubin level is also slightly high, but i wouldn't consider it problematic.
For the moment, your blood lipid fractions are in their normal range. Since your treating doctor has considered reasonable stoping your medication, I would suggest you to monitor your cholesterol level, and if it starts to increase despite your diet, I would recommend you to start rosuvastatin, which is considered the drug of choice for treating high blood cholesterol.
In addition to low fat diet that you are following, I would also recommend to you physical exercise, like 30 minutes walking a day, avoiding meet, dairy, , deep fried foods, and egg yolks and try to eat green or dark green leafy vegetables and fruit, and try healthy alternatives of cooking, such as baking, broiling and roasting.

Hope I helped with my answer. For further concerns, please feel free to ask again.

Take Care,
Dr. Ina
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What Is The Treatment To Lower The SGOT And SGPT Values?

Hello, Thank you for your question and welcome to Health Care Magic. I read carefully your query and I understand your concerns. Increment of liver enzymes is a known side effect of the usage of statins, which are medications used for lowering blood cholesterol. Two liver enzymes in particular (SGPT or ALT, and SGOT or AST) may be mildly elevated, but in my opinion it is safe to continue treatment unless they rise by three times the upper limit of normal and in that case the statin should be stopped. The damage is not permanent and when statins are stopped the liver tests return to normal. Normal values of SGPT are considered 5 -50 U/L and for SGOT- 7-40 U/L. Bilirubin level is also slightly high, but i wouldn t consider it problematic. For the moment, your blood lipid fractions are in their normal range. Since your treating doctor has considered reasonable stoping your medication, I would suggest you to monitor your cholesterol level, and if it starts to increase despite your diet, I would recommend you to start rosuvastatin, which is considered the drug of choice for treating high blood cholesterol. In addition to low fat diet that you are following, I would also recommend to you physical exercise, like 30 minutes walking a day, avoiding meet, dairy, , deep fried foods, and egg yolks and try to eat green or dark green leafy vegetables and fruit, and try healthy alternatives of cooking, such as baking, broiling and roasting. Hope I helped with my answer. For further concerns, please feel free to ask again. Take Care, Dr. Ina