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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Is The Treatment For Nephrotic Syndrome?

hi my daughter has diagnose with nephrotic syndrome since july 06 she has been on prednisone since then she is now tapering of and she is on 1ml and will stop thuesday. she is put on cyclopporine about two monhts which is very scary based on the side effect . now she must do her shots this morning but is it safe for her to do her shots now

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Tue, 16 Feb 2016
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General & Family Physician 's  Response
Hi thanks for asking question.
You have not mentioned whether renal biopsy has been done or not.
Mostly in children nephrotic syndrome is due to minimal change disease.
Steroid is excellent effective in such cases.
Steroid prednisolone taken as dose 2mg/kg/day for 4 to 6 week.
Then 1.5 mg/kg/day for another 4 to 6 week.And with lowering dose alternate day for another 2 to 4 month.Total 12 week therapy may needed.
If relapse occurs then usually cyclosporin used.
Few side effect of cyclosporin are gum hyperplasia,bleeding gum,tingling and numbness,tremor ,vomitting etc.
Low salt diet taken.
I hope you understand my concern.
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What Is The Treatment For Nephrotic Syndrome?

Hi thanks for asking question. You have not mentioned whether renal biopsy has been done or not. Mostly in children nephrotic syndrome is due to minimal change disease. Steroid is excellent effective in such cases. Steroid prednisolone taken as dose 2mg/kg/day for 4 to 6 week. Then 1.5 mg/kg/day for another 4 to 6 week.And with lowering dose alternate day for another 2 to 4 month.Total 12 week therapy may needed. If relapse occurs then usually cyclosporin used. Few side effect of cyclosporin are gum hyperplasia,bleeding gum,tingling and numbness,tremor ,vomitting etc. Low salt diet taken. I hope you understand my concern.