Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
140 Doctors are Online

What is the reason for dosage of Oxyteracycline, in terms of bioavailability and absorption?

hi I was wondering if you tell me why Oxyteracycline is given 250mg QDS at 6 hour intervals for 7 days, in terms of bioavaliblity and absoption, distribution and clearence ie how it relates to blood levels (theraputic)
Asked On : Sat, 24 Mar 2012
Answers:  1 Views:  25
Report Abuse
Share on Facebook
Share on Twitter
Share on Google+
Question is related to
Medical Topics
General & Family Physician 's  Response
Hi, thanks for your query.
Tetracyclines mainly differ in their absorption and elimination when given orally. Oxytetracycline has a moderate degree of absorption with the bioavailability of 60 to 70 %. It is widely distributed.
It is a short acting tetracycline as its serum half life is about 6 to 8 hours. Serum half life is the time taken for the drug to be reduced in to half of its original concentration. This determines the frequency (how many times the drug needs to be given daily) of drug administration.
Proper maintainence of plasma level of a drug is necessary to achieve an effective therapeutic benefit and to prevent unnecessary side effects.Dose of the drug determines this.
Since Oxytetracycline is a short acting drug with rapid elimination rate, it has to be given as 250mg per day at four times a day .
Hope I have answered your query.
Answered: Sun, 31 Mar 2013
I find this answer helpful

3 Doctors agree with this answer

Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]


Loading Online Doctors....
© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor