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Dr. Andrew Rynne

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What is the effect of thyroid hormone on menstruation?

hi Doctors... i m a 23 years old medical student and i just need a clarification about the effect of thyroid hormone on menstruation...it s 4 my exam... my Question specifically is how does menorrhagia occur in 1ry hypothyroidism? what is the exact mechanism ?? thxx in advance :)
Wed, 27 Feb 2019
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Endocrinologist 's  Response
Hello,

Hypothyroidism may classically cause menorrhagia, probably as a consequence of anovulatory dysfunctional uterine bleeding, but it is a rare cause of this symptom.

Most women with untreated hypothyroidism will develop amenorrhoea. The connection between thyroid hormone levels and the menstrual cycle is mainly mediated by thyrotropin-releasing hormone (TRH), which has a direct effect on the ovary.

Additionally, abnormal thyroid function can alter levels of sex hormone-binding globulin, prolactin, and gonadotropin-releasing hormone, contributing to menstrual dysfunction.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Elona Xhardo, Endocrinologist
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What is the effect of thyroid hormone on menstruation?

Hello, Hypothyroidism may classically cause menorrhagia, probably as a consequence of anovulatory dysfunctional uterine bleeding, but it is a rare cause of this symptom. Most women with untreated hypothyroidism will develop amenorrhoea. The connection between thyroid hormone levels and the menstrual cycle is mainly mediated by thyrotropin-releasing hormone (TRH), which has a direct effect on the ovary. Additionally, abnormal thyroid function can alter levels of sex hormone-binding globulin, prolactin, and gonadotropin-releasing hormone, contributing to menstrual dysfunction. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Elona Xhardo, Endocrinologist