Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
175 Doctors are Online

What is Acidosis and other related disorders ?

what is normal anion gap acidosis? what is reduced/negative anion gap acidosis? what is high anion gap? what is hypoproteinemia? give examples of each or the causes of each and their values.. thank you!
Asked On : Sat, 16 Jul 2011
Answers:  1 Views:  110
Report Abuse
Share on Facebook
Share on Twitter
Share on Google+
  User's Response
Anion gap provides an estimate of the unmeasured anions in plasma.

Anion gap = [Measured Cations(+ions)] - [Measured Anions(-ions)]

Normal anion gap acidosis is where in the blood pH is acidic (less than 7.35) and the anion gap (unmeasured anions) in normal (12 +/- 4 or 7 +/- 4 as per some labs). This is seen in Diarrhea (gastrointestinal bicarbonate loss), Renal tubular acidosis, and in intake of drugs like ammonium chloride, hydrochloric acid.

Reduced/negative anion gap acidosis is where in the blood pH is acidic and the anion gap is less than normal, seen in Hypoalbuminemia,
Hypercalcemia, Hyperkalemia, Hypermagnesemia, Lithium toxicity, Multiple Myeloma.

High anion gap is seen when the unmeasured anions are more as in conditions like Methanol Toxicity, Uremia, Diabetic Ketoacidosis, Lactic Acidosis, Dehydration. High anion gap is also seen when the unmeasured cations are decreased as in Hypocalcemia, Hypokalemia, Hypomagnesemia.

Hypoproteinemia is the condition where in the plasma proteins are
less than normal(6 to 8.3 gm/dl). One common cause is Protien loss in urine seen several Nephropathies.
Answered: Sat, 16 Jul 2011
I find this answer helpful

1 Doctor agrees with this answer

Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]


Loading Online Doctors....
© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor