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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does This Endometrial Biopsy Test Result Indicate?

HI about a month ago I had a Hysteroscopy, Dilation and Curettage and Hysteroscopic Resection of Polyp, Myosure. This was the Pathologic Findings. Fragments of Proliferative Endometrium and Benign Endometrial Tissue, Showing Glandular and Stromal Breakdown, Focal Fragments of Benign Endometrial Tissue Suggestive of Polyp. The biopsy found the following: Sections of endometrium focally approaching simple hyperplasia without cytologic atypia. Also noted are fragments of smooth muscle proliferation without any cytologic atypia or necrosis. There is a separate fragment of hypercelluar proliferation of spindle cells showing ovoid nucleus and scant eosinophilic cytoplasm with low activity. Immunistochemical stains performed show positive staining of the cellular spindle cell fragments with SMA, desmin and estrogen receptors; negeative staining with HMB-45, s100, p53 and p16, low Ki-67 activity. The differential diagnosis includes cellular leiomyoma or smooth muscle tumor of uncertain malignant potential. Can you please explain this to me. Especially concern of the last few sentences of tis diagnosis. Thanks
Mon, 31 Dec 2018
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OBGYN 's  Response
Hi,

Following is my reply:
1) This means there is a small mass hanging out which is polyp and does not seem to be cancer.
2) Please meet an oncologist in person.

Hope I have answered your query. Let me know if you need anymore help.

Regards,
Dr. Soumya, OBGYN
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What Does This Endometrial Biopsy Test Result Indicate?

Hi, Following is my reply: 1) This means there is a small mass hanging out which is polyp and does not seem to be cancer. 2) Please meet an oncologist in person. Hope I have answered your query. Let me know if you need anymore help. Regards, Dr. Soumya, OBGYN