Hello dear, thanks for your question on HCM. Your brother s recent biopsy report is suggestive of inflammation and absence of malignancy. This is actually good sign for him. His first biopsy confirmed the presence of poorly differentiated adenocarcinoma. After this he underwent chemotherapy. And now his recent biopsy is not showing any malignancy. This means chemotherapy has worked excellently and tumour burden is reduced. So his adenocarcinoma is highly chemo sensitive. And this is good sign for better survival and increased life expectancy.