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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does My Lab Test Report Indicate?

Hi All, I am Karan Bir. My mother is a breast cancer patient. A lump was identified in her breast about 9 months back. Then first she went through 8 cycles of chemotherapy (no biopsy before chemo, only memogram and FNAC was done) and clinician termed it as T4dN1M0. About a week back she underwent mastectomy and clinician sent mastectomy specimen for biopsy. The report is as under: Clinical Diagnosis: Ca. Breast. Gross: Received a mastectomy specimen measuring 18x16x6 cm with axillary tail measuring 14x5x2 and the overlying skin measuring 15x8cm. On serial slicing, a tumor is seen in the upper out quadrant measuring 3x3 cm extending 2 cm away from the DRP and far away from the nipple and areola. The skin is unremarkable. Adjacent breast, on serial slicing, doesn t reveal any other tumor. 10 lymphnodes identified. Micro: Section studied from breast shows areas of necrosed tumor cells with focal multinucleated giant cell reaction is seen, however there is no viable tumor cells identified. There are areas of dense sclerosis with chronic inflammatory infiltrate with multinucleate giant cells and focal area of lymphoid aggregate with areas of fat necrosis identified. Deep resection plane is free of tumor. Nipple areola and overlying skin are unremarkable. Eleven identified and free of tumor. Please explain me what is all there in this report in laymen language. Thank you.
Thu, 8 Jun 2017
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General Surgeon 's  Response
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.

Report is pretty good showing excellent response with chemotherapy. Problem is further marker study, ER, PR, AND HER2, not being done. We can plan hormonal treatment for that and she will require radiotherapy.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. B.dinesh
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What Does My Lab Test Report Indicate?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Report is pretty good showing excellent response with chemotherapy. Problem is further marker study, ER, PR, AND HER2, not being done. We can plan hormonal treatment for that and she will require radiotherapy. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. B.dinesh