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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does It Mean To Have A Positive Urinalysis Leukocyte Esterase Test Result While Suffering From Inflamed Kidneys?

A urinalysis LEUKOCYE ESTERASE test results are +3. Patient is seeing rheumatologist for autoimmune condition and currently taking cellcept. Is the +3 lab results due to 1) autoimmune condition (i.e., kidney inflammation), 2) cellcept, 3) kidney stone. Also, how critical is this condition? Patient is due to see internist next week; should we seek attention sooner?
Mon, 24 Aug 2015
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General & Family Physician 's  Response
Hello,
Welcome to Health Care Magic. I read carefully your query and I understand your concern.
Leukocyte esterase +3 mean that you have white blood cell in urine, this mean that you have a urinary tract infection. Leukocyte esterase is an enzyme present in white blood cell, the increasing of white blood test in urine increase and the esterase and when it happens it means a renal inflammation, the common cause is a bacterial urinary tract infection. To verify that you have urinary tract infection you should make and the nitrite test urine, if this is also positive it is sure that you have a urinary infection on bladder or kidney and you should do a culture to find the bacteria and to establish the antibiotic you should take.
It isn’t a side effect of cellcept(mycophenolate mofetil), cellcept urine side effect that can happen is blood at urine not white blood cell. Kidney stones can cause red blood cell urine presence so happen and for autoimmune renal inflammation.
You should go to your internist doctor to evaluate this problem for a better way, but don’t worry isn’t a critical condition.
Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. I will be happy to answer your questions.
Kind regard,
Dr .Marsida JANKO
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What Does It Mean To Have A Positive Urinalysis Leukocyte Esterase Test Result While Suffering From Inflamed Kidneys?

Hello, Welcome to Health Care Magic. I read carefully your query and I understand your concern. Leukocyte esterase +3 mean that you have white blood cell in urine, this mean that you have a urinary tract infection. Leukocyte esterase is an enzyme present in white blood cell, the increasing of white blood test in urine increase and the esterase and when it happens it means a renal inflammation, the common cause is a bacterial urinary tract infection. To verify that you have urinary tract infection you should make and the nitrite test urine, if this is also positive it is sure that you have a urinary infection on bladder or kidney and you should do a culture to find the bacteria and to establish the antibiotic you should take. It isn’t a side effect of cellcept(mycophenolate mofetil), cellcept urine side effect that can happen is blood at urine not white blood cell. Kidney stones can cause red blood cell urine presence so happen and for autoimmune renal inflammation. You should go to your internist doctor to evaluate this problem for a better way, but don’t worry isn’t a critical condition. Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. I will be happy to answer your questions. Kind regard, Dr .Marsida JANKO