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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does It Mean By Mild Shift To Left With Reactive Lymphocytes In Peripheral Smear Test?

Dear Sir, My daughter having sever head ache urinary infection and our consulting doctor advised to do several tests including Peripheral smear test. In the peripheral smear test Impression: very mild shift to left with reactive lymphosytes. RBC and platelets study within normal limits. may be seen in response to infection. What it mean by
Mon, 23 Jun 2014
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Pathologist and Microbiologist 's  Response
Hello and welcome to HCM,

Before understanding the term shift to left, you need to understand what neutrophils are.
Neutrophils are type of white blood cells which increase in cases of infection,
Normally only mature forms are seen on peripheral blood smear but in cases of infection, immature neutrophils are also present.
Presence of immature cells on peripheral blood smear is called shift to left.

You have mentioned that there is history of urinary tract infection, so urinary tract infection is the most probable cause of shift to left.
Reactive lymphocytosis is a condition characterized by presence of lymphocytes which reflect features of infection in blood.

Consult your primary he
alth provider for further work up and prescription of antibiotic for urinary tract infection.

Thanks and take care
Dr Shailja P Wahal
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What Does It Mean By Mild Shift To Left With Reactive Lymphocytes In Peripheral Smear Test?

Hello and welcome to HCM, Before understanding the term shift to left, you need to understand what neutrophils are. Neutrophils are type of white blood cells which increase in cases of infection, Normally only mature forms are seen on peripheral blood smear but in cases of infection, immature neutrophils are also present. Presence of immature cells on peripheral blood smear is called shift to left. You have mentioned that there is history of urinary tract infection, so urinary tract infection is the most probable cause of shift to left. Reactive lymphocytosis is a condition characterized by presence of lymphocytes which reflect features of infection in blood. Consult your primary he alth provider for further work up and prescription of antibiotic for urinary tract infection. Thanks and take care Dr Shailja P Wahal