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What does elevated SGPT with pain and swelling in the ankle in one with bone TB indicate ?

Hi Sir, My mother is having high level of SGPT - 130 and GGT 180. She is also suffering from Bone TB in her right ankle . Pain is there and it s also swallon.. Is there something to worry?
Asked On : Mon, 26 Mar 2012
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Orthopaedic Surgeon, Joint Replacement 's  Response
I would suggest you to take opinion from gastroenterologist as TB medicines, may cause damage to liver and that is the reason that liver enzymes are increasing? I would suggest you to stop isoniazid, rifampicin and pyrizinamide. Once liver enzyme are normal we can start these drugs one by one.
Answered: Fri, 21 Mar 2014
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