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What does a high ALT level mean? History of hemangioma

My ALT is at 403...what does this mean? Im not overweight, eat healthy, do not drink alcohol. Have had a hemangioma 1 1/2 years ago that was found accidentally when I had my gallbaldder removed. AM having arrythmias which my cardiologist has done one ablation so far. Could they be related. I also experience blood pressure spikes off and on...165/120. My ast is 147 and my phosphate is 142. What does this mean.. My creatine is 1.4 and borderline BUN. My WBC is elevated and my RBC is just below the range.
Asked On : Thu, 4 Oct 2012
Answers:  2 Views:  544
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Internal Medicine Specialist 's  Response
Dear friend, welcome and thanks for entrusting your query here at HCM !

Your ALT (alanine transferase) is high so also AST.
Both are liver cell enzymes and elevations indicates some liver injury.
It is seen in N number of disorders of the liver. Gall bladder disease, drugs, infections etc. can cause it.

What medicines are you on?
Do you have jaundice, fever, right upper abdominal pain?

Your borderline parameters suggest something still wrong--? residual infection?
I would suggest a thorough evaluation for liver, gall bladder, pancreas, USG abdomen, drugs review for liver toxicity, other liver markers etc.

Please get a GI opinion.
keep me informed on your progress.

I hope you are fully satisfied with the guidance I gave.
I would be glad to answer any further queries.
Thank you and Good luck !
Answered: Fri, 5 Oct 2012
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Pathologist and Microbiologist Dr. Shailja Puri 's  Response
Hello and welcome to HCM
The information that I get is that you have high ALT(403) and high AST(147) levels.
The level of ALT is higher than AST. This profile indicates a chronic liver disease.
Hemangioma is unrelated with these findings as it is a benign lesion which does not interfere with the functioning of liver cells.
These two enzymes AST and ALT are increased when liver cells are damaged by any disease.
You have mentioned phosphate level as 147 which I interpret as alkaline phosphatase (ALP). If this is the value of ALP, then it is within normal limits, however on higher side of the range.

These findings are unrelated to cardiac arrythmia or hypertension.

You need to get your complete liver function tests which includes total proteins, albumin, total & direct bilirubin, alkaline phosphatase (if not done), gamma glutamyl transferase and 5- nucleotidase.
Do consult your physician after getting these tests done.

Thanks and take care
Dr Shailja P Wahal
Answered: Thu, 4 Oct 2012
I find this answer helpful
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