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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does HBsAg-reactive And Anti HBs-non Reactive Suggest?

my son has hepa b hbsag-reactive-anti hbs-non reaetive-anti hbc-lgg-reactive- anti hbc lgm-non reactive -Hbeagnon reactive -anti =hbe-reactive -my son 32 years and it was detect 2007 -this profile is last july 5 2014 what is the meaning of this-thank you?
Mon, 27 Apr 2015
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General & Family Physician,  's  Response
Hi, I had gone through your question and understand your concerns.

Let me analyse your reports-

1.HBsAg - reactive (HBsAg is a marker of both acute and chronic HepB infection)
2.IgM antiHBc - nonreactive , IgG antiHBc - reactive ( IgM antiHbc is a marker of acute infection , IgG is a marker of chronic infection)
3.Hbe Ag- nonreactive ( HbeAg is one of the quantitative markers of the viral replication)
4.Anti Hbs - nonreactive ( Anti Hbs indicates complete recovery from HepB infection)

This actually points towards - HBe nonreactive chronic hepatitis B.

There are plenty of medications available like Entecavir , Pegylated Interferon and others. They can be started based on the HBV DNA level and SGOT,SGPT level.

Do not worry.

It would have been great had I examined him on my own.
I would suggest you to take him to a gastro-enterologist . He/she can examine him and correlate clinically.

Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. I will be happy to answer your questions.

Wishing your son's good health.
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What Does HBsAg-reactive And Anti HBs-non Reactive Suggest?

Hi, I had gone through your question and understand your concerns. Let me analyse your reports- 1.HBsAg - reactive (HBsAg is a marker of both acute and chronic HepB infection) 2.IgM antiHBc - nonreactive , IgG antiHBc - reactive ( IgM antiHbc is a marker of acute infection , IgG is a marker of chronic infection) 3.Hbe Ag- nonreactive ( HbeAg is one of the quantitative markers of the viral replication) 4.Anti Hbs - nonreactive ( Anti Hbs indicates complete recovery from HepB infection) This actually points towards - HBe nonreactive chronic hepatitis B. There are plenty of medications available like Entecavir , Pegylated Interferon and others. They can be started based on the HBV DNA level and SGOT,SGPT level. Do not worry. It would have been great had I examined him on my own. I would suggest you to take him to a gastro-enterologist . He/she can examine him and correlate clinically. Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. I will be happy to answer your questions. Wishing your son s good health.