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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Do These SGOT And SGPT Levels Indicate?

My brother is not feeling well and just received lab reports where is sgot and sgpt levels are extremely high i.e. AST (SGOT) is 48 Range 5-34 ALT (SGPT) is 117 Range 0-55 He does not drink alcohol,take heavy tylenol. He also high creatine levels, been losing weight etc.. everything I read leans toward Hepatitis or some type of poisoning. He also shows signs of Hyperthryoid and has been losing weight even with increase eating. I am concerned he has been exposed to some type of chemical, poison or could it be related to the something else. Should docs test him for Hepatitis? Please let me know other tests they should be running with with these results. 54 year old male, very athletic and lean. A Ultrasound has been scheduled of his Thyroid too. Other symptoms, heart palpitations, dry skin, hair loss throughout top part of hair, evenly and mood swings. Thanks of any help on this.
Mon, 29 Jun 2015
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General & Family Physician,  's  Response
Thanks for yoyr consultation at HCM :
I have gone through your case history thoroughly..
Your brother has got deranged liver funtions and signs and symptoms of hyperthyroidism..
As far as liver is concerned , he should be screened for any liver pathology which is causing derangement in LFTs...As u mentioned that he is not alcoholic but there are still other causes which can affect liver like viral infections < hav , hbv, hcv > AUTOIMMIUNE DISORDERS , metabollic disorders and last but not the least is FATTY LIVER DISEASE.TYLENOL may cause deranges LFTs if taken in large doses...You should consult hepatologist so that exact cause of deranged liver function can be sort out.
Secondly, for the symptoms of HYPERTHYROIDISM he should have his THYROID FUNCTION TESTS done along with TSH levels...Apart from this THYROID scan should be done.. consult endocrinologist regarding this issue...
Hope you have got your answer if u have got any querries feel free to ask anytime
REGARDS
DR SAAD SULTAN
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What Do These SGOT And SGPT Levels Indicate?

Thanks for yoyr consultation at HCM : I have gone through your case history thoroughly.. Your brother has got deranged liver funtions and signs and symptoms of hyperthyroidism.. As far as liver is concerned , he should be screened for any liver pathology which is causing derangement in LFTs...As u mentioned that he is not alcoholic but there are still other causes which can affect liver like viral infections hav , hbv, hcv AUTOIMMIUNE DISORDERS , metabollic disorders and last but not the least is FATTY LIVER DISEASE.TYLENOL may cause deranges LFTs if taken in large doses...You should consult hepatologist so that exact cause of deranged liver function can be sort out. Secondly, for the symptoms of HYPERTHYROIDISM he should have his THYROID FUNCTION TESTS done along with TSH levels...Apart from this THYROID scan should be done.. consult endocrinologist regarding this issue... Hope you have got your answer if u have got any querries feel free to ask anytime REGARDS DR SAAD SULTAN