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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Could Be Done To Wean Off Clozapine Without Which Vertigo Starts?

I have been taking .05 Clozapine twice a day for a year to treat Vertigo which was quite severe 3 years ago. Meclizine did not help but Clozapine does. In addition to that, I take Ambien 2-3 times a week for sleep. I was also drinking 2-3 ounces of Vodka nightly which I have discontinued. My plan is to wean myself off Ambien but am not sure about Clozapine because when I don t take it, my head starts spinning again.
Tue, 27 Nov 2018
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Neurologist 's  Response
Hello,

If you have vertigo that has never been evaluated as to underlying then, I suggest you see a neurologist or if possible a NEURO-OTOLOGIST.

There must be a reasonable explanation for why you have such symptoms that can only be cured with clozapine.

You should be screened for what is known as VERTEBROBASILAR INSUFFICIENCY which is a reduction or lack of good perfusion into the vascular tree of the brainstem which could be critical.

It should not be masked by something like clozapine but rather identified and addressed.

Perhaps, it is something simple such as BENIGN PAROXYSMAL POSITIONAL VERTIGO (BPPV) which can also be quieted down by something like clozapine but never cured as well as either the Brandt-Daroff exercises or an Epley Maneuver.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Dariush Saghafi, Neurologist
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What Could Be Done To Wean Off Clozapine Without Which Vertigo Starts?

Hello, If you have vertigo that has never been evaluated as to underlying then, I suggest you see a neurologist or if possible a NEURO-OTOLOGIST. There must be a reasonable explanation for why you have such symptoms that can only be cured with clozapine. You should be screened for what is known as VERTEBROBASILAR INSUFFICIENCY which is a reduction or lack of good perfusion into the vascular tree of the brainstem which could be critical. It should not be masked by something like clozapine but rather identified and addressed. Perhaps, it is something simple such as BENIGN PAROXYSMAL POSITIONAL VERTIGO (BPPV) which can also be quieted down by something like clozapine but never cured as well as either the Brandt-Daroff exercises or an Epley Maneuver. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Dariush Saghafi, Neurologist