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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Seizures In Babies With Loss Of Development?

I have a 3 year old daughter who has seizures at 6 months of age and lost all developmental and cognitive abilites. She is slowly gaining them back at is at this time functionally at a 1 1/2 to 2 year old. We have had mris and catscans done and all is well we have had e.e.g s done and they are improving. She was born with a low sugar level of 24 and otherwise was ok. She has been seizure free for 2 and 1/2 years and was on topamax for 2 years. She is dealing with the side effects of that now. She is currently on keppra 1.5 ml bid as a preventive measure. what could cause a baby to have seizures and then they go away but leave such a bad path. I see her improving daily. We have had tests ran and nothing comes up no cerebral palsy chromosomal or metabolic. Please help.
Fri, 10 Apr 2020
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Pediatrician 's  Response
Hi,

Seizure and loss of already attained milestones occur in a condition called neuro-degenerative disorder. Truly speaking, this is not a single disease but a group of conditions with neuro-regression. Frequently, despite thorough investigations, we won't be able to find out a specific course, as new diseases are being discovered year by year and the list we have now is incomplete and yet to expand.

The hypoglycemia she had after delivery could be a reason, but in that case we expect MRI to be abnormal and although milestones can be delayed, loss of already gained ones is unusual. In such cases, what we can offer is symptoms oriented supportive measures like early stimulation to maximise development, seizure control with drugs, maintain proper nutrition, vision and hearing assessment and management. Your doctor will guide through these steps.

Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Muhammed Aslam TK, Pediatrician
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What Causes Seizures In Babies With Loss Of Development?

Hi, Seizure and loss of already attained milestones occur in a condition called neuro-degenerative disorder. Truly speaking, this is not a single disease but a group of conditions with neuro-regression. Frequently, despite thorough investigations, we won t be able to find out a specific course, as new diseases are being discovered year by year and the list we have now is incomplete and yet to expand. The hypoglycemia she had after delivery could be a reason, but in that case we expect MRI to be abnormal and although milestones can be delayed, loss of already gained ones is unusual. In such cases, what we can offer is symptoms oriented supportive measures like early stimulation to maximise development, seizure control with drugs, maintain proper nutrition, vision and hearing assessment and management. Your doctor will guide through these steps. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Muhammed Aslam TK, Pediatrician