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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What causes rise in the AST and ALT levels?

Hi. I hope someone can tell me Im paranoid. Heres the facts- 1) I weight train and based on studies...this has been proven to increase both AST and ALT. Both of these markers always at the high end and sometimes double. As we know, high liver enzyme activity isnt the only markers we should look at to conclude REAL LIVER DAMAGE...caused by chemicals. You gotta consider BILIRUBIN n GGT. These two are always normal. I am 40 years old. 2) I take nimetazepam and a joint every night.3) Since all the other markers are normal. Only AST n ALT are high...but these readings are high likely due to -Weight-training causes ALT n AST to increase but taking into account BILIRUBIN n GGT which are true markers of PATHOLOGICAL DAMAGE. Mine are good.Marijuana may stimulate enzyme activity,Benzodiazepines will increase them ALT N AST. Everything else is good. Should i be worried? PLEASE HELP. IM PARANOID.
Mon, 17 Apr 2017
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General Surgeon 's  Response
Hi, I had gone through your question and understand your concerns.

AST and ALT are sensitive indicators of liver damage or injury from different types of diseases or conditions, and collectively they are termed liver tests or liver blood tests. So the next step is to look for certain liver damage and most common cause is fatty liver disease. It should be confirmed by ultrasound. Other causes are viral hepatitis,cirrhosis, medications, alcohol intake or autoimmune diseases. To verify exact cause, US, bilirubin levels and tumor markers should be additionaly done Then appropriate treatment can be started. For a start, Eat a balanced and healthy diet and get regular exercise. Limit high-carb foods such as bread, grits, rice, potatoes, and corn. And cut down on drinks with lots of sugar like sports drinks and juice.

Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. I will be happy to answer your questions.

Wishing you good health.
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What causes rise in the AST and ALT levels?

Hi, I had gone through your question and understand your concerns. AST and ALT are sensitive indicators of liver damage or injury from different types of diseases or conditions, and collectively they are termed liver tests or liver blood tests. So the next step is to look for certain liver damage and most common cause is fatty liver disease. It should be confirmed by ultrasound. Other causes are viral hepatitis,cirrhosis, medications, alcohol intake or autoimmune diseases. To verify exact cause, US, bilirubin levels and tumor markers should be additionaly done Then appropriate treatment can be started. For a start, Eat a balanced and healthy diet and get regular exercise. Limit high-carb foods such as bread, grits, rice, potatoes, and corn. And cut down on drinks with lots of sugar like sports drinks and juice. Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. I will be happy to answer your questions. Wishing you good health.