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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Palpitations And Disorientation After Quitting Lamotrigine?

My wife has been on lamotrigine for a year and a half to treat bipolar disorder. 200mg daily About a week ago she decided to stop taking it and not tell me. Today she came home crying and said her head felt like it was going to explode. She said her mind was racing and had been for 2 days. Severe manic episode. She seemed disoriented, rattled, and scared. I ran her a warm bath and she listened to soon soft music and calmed down. She feels she definitely needs to start taking it again but is not sure she should start a 200mg dose daily after missing 6 days. Would it be ok for her to begin her regular dose again after missing that many doses?
Mon, 2 Jul 2018
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Neurologist, Surgical 's  Response
Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.

Drugs like Lamotrigine should not be stopped suddenly, if the decision of the Doctor is to stop it, it should be tapered. Even after 6 days, it is necessary to start the treatment again with the same doses in order to return to the previous state.

Hope I have answered your query. Let me know if I can assist you further.
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What Causes Palpitations And Disorientation After Quitting Lamotrigine?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Drugs like Lamotrigine should not be stopped suddenly, if the decision of the Doctor is to stop it, it should be tapered. Even after 6 days, it is necessary to start the treatment again with the same doses in order to return to the previous state. Hope I have answered your query. Let me know if I can assist you further.