Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. I have gone through the medical history of your beloved wife and understood your concern. Pain behind right eye, severe headache in temple/ear/eye area on right side associated with yellow discharge from right ear is suggestive of purulent otitis (infection of outer or inner ear). A good ENT examination is highly recommended. She might need prescription antibiotics orally and prescription ear drop preparations locally. However, ENT specialist is the only one who can prescribe them after a good examination. Get her checked as soon as possible to prevent severe side effects. Hope I have answered your query. Let me know if I can assist you further.