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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Low WBC Count And Fatigue?

My 75 year old brother-in-law has a low white blood count, chief complaint is fatigue. Otherwise, feels fine. Originally his family doctor thought the low WBC was due to his medicine for history of seizures and changed meds. Hematologist did a bone marrow biopsy on Friday to rule out aplastic anemia or leukemia and he will get the results on Wednesday. What else could cause his symptoms? He has had heart bypass surgery and non-cancer colon surgery about 8-10 years ago. THANKS!
Mon, 27 Oct 2014
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Geriatrics Specialist 's  Response
Hi,
Thanks for asking.
Based on your query, my opinion is as follows.
1. Only WBC count increase does not indicate aplastic anemia.
2. All the cell counts should be reduced for a possible diagnosis of aplastic anemia.
3. Bone marrow biopsy could show occupying lesions. However, fibrosis or other causes require evaluation.
Hope it helps.
Any further queries, happy to help again
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What Causes Low WBC Count And Fatigue?

Hi, Thanks for asking. Based on your query, my opinion is as follows. 1. Only WBC count increase does not indicate aplastic anemia. 2. All the cell counts should be reduced for a possible diagnosis of aplastic anemia. 3. Bone marrow biopsy could show occupying lesions. However, fibrosis or other causes require evaluation. Hope it helps. Any further queries, happy to help again