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Dr. Andrew Rynne
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What causes high erythrocyte sedimentation rate?

Hi, My wife s rheumatologist did some test and she was at the clinic and they told her she had a really high sed rate. She has been feeling a lot of pain in her joints and the rheumatologist said it was her fibro was really active. What does a very high sed rate mean?
Tue, 18 Oct 2016
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General & Family Physician 's  Response
Hi & Welcome.
I appreciate your concern for your beloved wife.

A high ESR associated with painful joints is suggestive of acute flare up of the inflammatory arthritis like rheumatoid arthritis.

She needs to be evaluated by a rheumatologist for certain lab tests such as Rh factor, C reactive protein, ASO titre, Anti-nuclear antibodies, Anti-smooth muscle antibodies, Anti-CCP, etc.

She may need a short course of Prednisone followed by anti rheumatoid drugs like Methotrexate or Hydrooxychloroquine for her painful joints.

Hope this will help.
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