Hello! Thank you for asking on HCM! Her symptoms could be related to different disorders: - migraine - high blood pressure - inflammation The nose bleeding and the loss in her weigh is concerning for possible intracranial lesion or a tumor. I recommend to closely monitor her blood pressure and refer to her attending physician. High blood pressure can lead to headaches and nose bleeding. Besides a careful physical exam, some tests are needed: - chest X ray study - abdominal ultrasound - lab blood tests (complete blood count, thyroid hormone levels, PCR, sedimentation rate, coagulation tests) - a brain CT scan to exclude possible intracranial lesion. Hope to have been helpful! Best wishes, Dr. Aida