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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Elevation In TLC And Neutrophil Count?

Hello Sir/Madam, My dad (58 yrs) has high TLC (12600) & High Neutrophils (79%). He is diabetic (under control), has cholesterol (under control), is obese. He had edema in his legs for which he was put on Torsemide 10mg from 18th May 2014. But, his Serum Creatnine & S. Urea are high (1.43 & 46.4 respectively). He was put on Levofloxacin-Azithromycin too (5 days) but that didn t reduce the TLC. What could be wrong?
Mon, 10 Nov 2014
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General & Family Physician,  's  Response
Hello
The TLC is 12600 cmm ( normal 4000-10000 or 11000 /cmm),while neutrophils count is 79%(40-75 ).
However these both reading are slightly elevated but not alarming and also non-specific .
Even in elderly , diabetic patient mild infection may elevate up to this level , so specially no treatment require for this.
However , periodical check up of these two reading are important in every 3 months , if further increase then consult a physician .
Now about serum creatinine and blood urea level , although both levels are normal but upper limit .
Your father is taking torsemide (torasemide) and the side effects of torsemide are :
electrolytes disturbance , confusion state , loss of appetite, INCREASED SERUM URIC ACID , GLUCOSE , UREA & CREATININE ,LIPIDS . Also increases LFTs.
So for serum creatinine and urea level need not to worry .
Once you stop the torasemide , as long as no medical concern , these levels will come down.
Hope this will help you.
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What Causes Elevation In TLC And Neutrophil Count?

Hello The TLC is 12600 cmm ( normal 4000-10000 or 11000 /cmm),while neutrophils count is 79%(40-75 ). However these both reading are slightly elevated but not alarming and also non-specific . Even in elderly , diabetic patient mild infection may elevate up to this level , so specially no treatment require for this. However , periodical check up of these two reading are important in every 3 months , if further increase then consult a physician . Now about serum creatinine and blood urea level , although both levels are normal but upper limit . Your father is taking torsemide (torasemide) and the side effects of torsemide are : electrolytes disturbance , confusion state , loss of appetite, INCREASED SERUM URIC ACID , GLUCOSE , UREA & CREATININE ,LIPIDS . Also increases LFTs. So for serum creatinine and urea level need not to worry . Once you stop the torasemide , as long as no medical concern , these levels will come down. Hope this will help you.