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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Elevated Liver Enzymes?

Dear Sir, I am Rahul from Ludhiana, Punjab (46 Year Male) and recently I have done my LFT and there is is SGPT found elevated and other values are in normal range. SGPT result is 41. Also I wish to bring in your kind notice that I take 1-2 drinks daily. PLease help me in advising if there is any danger or I have to take further precautions. Further I am taking Zentak or Pantocid regularly due to frequent Gastric Problem Also I am taking Citrizine or Montair LC due to Freuent Allergy. Please advise further if there is anything to worry about elevated SGPT
Mon, 12 Dec 2016
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Addiction Medicine Specialist,  's  Response
first, liver enzyme elevations have to be put into context. Slight elevations only slightly over the lab normal values are not very much of a problem. Then, there are different patterns. There are different patterns from if the liver outflow is bad or if the cells are damaged. The bilirubin is elevated if outflow is affected. The liver cellular enzymes are elevated if it is liver cell death. You seem to be descrbing a situaiton n which only the liver cellular enzymes are elevated. This would be liver cell death BUT if it is only slight elevation it is only slight liver cel death. Any alcohol intake will cause some liver death. this can be bad over many years and cane lead to a non-functioning liver that is replaced by scar. This is not liklely.

Then there are the gastric problems. Those could be signs of liver injury/liver sickness. A biopsy or a simple ultrasound could show quite a lot .. starting with how much liver versus how much scar.
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What Causes Elevated Liver Enzymes?

first, liver enzyme elevations have to be put into context. Slight elevations only slightly over the lab normal values are not very much of a problem. Then, there are different patterns. There are different patterns from if the liver outflow is bad or if the cells are damaged. The bilirubin is elevated if outflow is affected. The liver cellular enzymes are elevated if it is liver cell death. You seem to be descrbing a situaiton n which only the liver cellular enzymes are elevated. This would be liver cell death BUT if it is only slight elevation it is only slight liver cel death. Any alcohol intake will cause some liver death. this can be bad over many years and cane lead to a non-functioning liver that is replaced by scar. This is not liklely. Then there are the gastric problems. Those could be signs of liver injury/liver sickness. A biopsy or a simple ultrasound could show quite a lot .. starting with how much liver versus how much scar.