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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Elevated Alkaline Phosphatase Levels?

Hi I am a 39 year old female 5 4 170 pounds. After I had my first child 9 years ago it was discovered my alkaline phosphatases were extremely elevated. I have had ultrasounds, biopsy, all kinds of tests done and no findings. I am stumped. I went in last week and had another check up and my ggt is 338, alkaline phos is 146 and my alt is 68. Everything else was normal. What if we never discover what it is ? Is this something that could potentially cause me to injure my liver permanently ? It freaks me out when the doctors just say we will keep monitoring it. I want to know what it is so I can fix it.
Tue, 18 Sep 2018
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General Surgeon,  's  Response
Hi,

Liver enzymes may be raised because of various causes. In your case some may be more possible but in every case it requires evaluation of the cause.

Most common causes of such liver derangement's are Alcohol, Viral hepatitis, Non-alcoholic fatty liver disease, Drugs.

Gamma GT is most commonly raised due to alcohol intake and in case you take alcohol, you need to keep a control over it.

If you don't take it, you need following tests: hepatitis virus markers, Ultrasound Abdomen and HIDA scan. A lot many times, the liver dysfunction is due to Non Alcoholic Fatty Liver Disease (NAFLD).

So, if you have any evidence of fatty liver in Ultrasound and your other tests are negative, this rise is liver enzyme would be attributed to NAFLD.

For this, you need to reduce your weight, reduce fat in the diet. This is my personal opinion based on details available here. If you still have any other query, you may please ask me. Stay Healthy.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Ivan R. Rommstein, General Surgeon
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What Causes Elevated Alkaline Phosphatase Levels?

Hi, Liver enzymes may be raised because of various causes. In your case some may be more possible but in every case it requires evaluation of the cause. Most common causes of such liver derangement s are Alcohol, Viral hepatitis, Non-alcoholic fatty liver disease, Drugs. Gamma GT is most commonly raised due to alcohol intake and in case you take alcohol, you need to keep a control over it. If you don t take it, you need following tests: hepatitis virus markers, Ultrasound Abdomen and HIDA scan. A lot many times, the liver dysfunction is due to Non Alcoholic Fatty Liver Disease (NAFLD). So, if you have any evidence of fatty liver in Ultrasound and your other tests are negative, this rise is liver enzyme would be attributed to NAFLD. For this, you need to reduce your weight, reduce fat in the diet. This is my personal opinion based on details available here. If you still have any other query, you may please ask me. Stay Healthy. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Ivan R. Rommstein, General Surgeon