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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Elevated PSA Levels?

I just had a PSA test with results of 9.13, up from about 5 6 to 12 months ago. I am 66 yrs old in good health. I have had an enlarged prostate for several years with no problems except going to pee once a night and sometimes not emptying completely. Within the past year I started taking 5mg day of Lisinopril, I also take 750mg of metformin and 20mg of pravastatin and baby aspirin daily and have for the past 2 or 3 years. Could any of these or their combination cause a high 9.13 PSA number?
Fri, 16 Mar 2018
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General & Family Physician,  's  Response
Hello,

Prostate-specific antigen (PSA) is a protein produced by the prostate gland. Its normal value for 60 to 69 years old men is 0 to 4.0 ng/mL.

Elevated levels of PSA can be caused by:
1. An enlarged prostate and prostate inflammation (prostatitis)
2. Urinary tract infection
3. Prostate cancer

Since, your PSA level continues to rise over a period of 12 months I advise you to consult a urologist for further evaluation.

Your doctor may recommend additional tests to determine the nature of the problem. A urine test may be recommended to check for a urinary tract infection, transrectal ultrasound, x-rays, or cystoscopy. A transrectal biopsy may also be done by your doctor to rule out prostate cancer.

None of the prescribed medications can elevate the PSA levels.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Mohammed Taher Ali
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What Causes Elevated PSA Levels?

Hello, Prostate-specific antigen (PSA) is a protein produced by the prostate gland. Its normal value for 60 to 69 years old men is 0 to 4.0 ng/mL. Elevated levels of PSA can be caused by: 1. An enlarged prostate and prostate inflammation (prostatitis) 2. Urinary tract infection 3. Prostate cancer Since, your PSA level continues to rise over a period of 12 months I advise you to consult a urologist for further evaluation. Your doctor may recommend additional tests to determine the nature of the problem. A urine test may be recommended to check for a urinary tract infection, transrectal ultrasound, x-rays, or cystoscopy. A transrectal biopsy may also be done by your doctor to rule out prostate cancer. None of the prescribed medications can elevate the PSA levels. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Mohammed Taher Ali