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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes Dizziness While On Clonidine?

My cardiologist has prescribed clonidine 0.1 to take prn when my systolic blood pressure goes above 160. It has happened to me twice in the last year. The first time it made me very dizzy and drowsy and i ended up sleeping the whole night. The second time, I felt dizzy and a funny feeling of being drowsy but not being able to sleep at all, all night, making me very tired. Tonight is another night that my bp is 165/90 and I have to take it. I m hesitant because of the lack of sleep the second time. Anything I can do if that happens? I m a 72-yr old female in generally good health. I do an hour of serious exercises 5 days a week. I m on Lisiniprol/HCTZ (10/12.5mg), Xarelto 20mg, and Metoprolol 25mg tid i do have a small aneurysm in the brain that my cardiovascular surgeon has said doesn t need any intervention. Normally my bp is kept between 120/75 -110/65 with the medication. I m not experiencing any more stress at this point than normal. The only difference now is seasonal allergies.
Fri, 19 May 2017
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General & Family Physician 's  Response
Hello Dear
I evaluated your concern deeply .
@ Clonidine is centrally acting Alpha 2 adrenergic , imidazoline receptor
agonist
leading to - decreased peripheral vascular resistance - lowering BP
- inhibit norepinephrine release - decrease presynaptic calcium
- target vasomotor center in brainstem - decrease
sympathetic tone
Combined effects of all lead to dizziness , more profound in your case
as you are already taking other anti hypertensive molecules also.
Hope this will definitely clear your query.
Feel free to ask any health related questions in future anytime .
Thanks for using Health care magic .
Regards dear .
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What Causes Dizziness While On Clonidine?

Hello Dear I evaluated your concern deeply . @ Clonidine is centrally acting Alpha 2 adrenergic , imidazoline receptor agonist leading to - decreased peripheral vascular resistance - lowering BP - inhibit norepinephrine release - decrease presynaptic calcium - target vasomotor center in brainstem - decrease sympathetic tone Combined effects of all lead to dizziness , more profound in your case as you are already taking other anti hypertensive molecules also. Hope this will definitely clear your query. Feel free to ask any health related questions in future anytime . Thanks for using Health care magic . Regards dear .