Hi, Medicines like Klonopin and Ativan are benzodiazepines. These can help in anxiety but cannot reduce depression. I agree with you that your husband appears to be quite depressed. He will need treatment with antidepressants like SSRIs (Zoloft, Prozac, Lexapro etc) or SNRIs (Effexor, Cymbalta etc). Depression is quite common in people with chronic neurological illnesses and treating it makes a lot of difference in the patient s quality of life. Please discuss this with his doctor and ensure that he gets the best treatment. Best wishes.