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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Causes An Increase In SGOT And SGPT Levels?

hello doctor,
i was taking terbinafine for fungal infection. after 5 weeks i checked my LFT which showed bil-1.9, with little increase in ot & pt levels, & within range alp levels. i need to know about what diet should i take. do i need any medication for this. it seems to be drug-induced.
regards,
i hussain
Wed, 30 Dec 2015
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Gastroenterologist,  's  Response
Hello. Thanks for putting your query in HCM.

I can understand your concerns.

Elevation of liver enzymes suggest liver cell injury. And there are many causes for the elevation of liver enzymes like alcohol intake, hepatitis, infection, drug induced etc.

Terbinafine itself can lead to increase in liver enzymes. So I will advise you to stop terbinafine and monitor your LFT once in a week. If they dont normalize may be after 2 months then visit a Gastroenterologist for evaluation

I hope I have answered your query and this will help you. If you have any further query I will be happy to answer that too. Remain in touch and get-well soon.
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What Causes An Increase In SGOT And SGPT Levels?

Hello. Thanks for putting your query in HCM. I can understand your concerns. Elevation of liver enzymes suggest liver cell injury. And there are many causes for the elevation of liver enzymes like alcohol intake, hepatitis, infection, drug induced etc. Terbinafine itself can lead to increase in liver enzymes. So I will advise you to stop terbinafine and monitor your LFT once in a week. If they dont normalize may be after 2 months then visit a Gastroenterologist for evaluation I hope I have answered your query and this will help you. If you have any further query I will be happy to answer that too. Remain in touch and get-well soon.